$GLOBALS['TYPO3_CONF_VARS'] = array_replace_recursive(
$GLOBALS['TYPO3_CONF_VARS'],
[
'SYS' => [
'caching' => [
'cacheConfigurations' => [
'pages' => [
'backend' => 'TYPO3\\CMS\\Core\\Cache\\Backend\\NullBackend',
'frontend' => 'TYPO3\\CMS\\Core\\Cache\\Frontend\\NullFrontend',
],
'rootline' => [
'backend' => 'TYPO3\\CMS\\Core\\Cache\\Backend\\NullBackend',
'frontend' => 'TYPO3\\CMS\\Core\\Cache\\Frontend\\NullFrontend',
],
'l10n' => [
'backend' => 'TYPO3\\CMS\\Core\\Cache\\Backend\\NullBackend',
'frontend' => 'TYPO3\\CMS\\Core\\Cache\\Frontend\\NullFrontend',
],
],
],
],
]
);